Application
MME Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the MME antibody detected the MME protein (arrow).Application
MME Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MME Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MME Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; Enkephalinase; Neutral endopeptidase 24.11; Skin fibroblast elastase; CD_antigen=CD10 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EPN |
|---|---|
| Alternative Names | MME EPN Neprilysin Atriopeptidase Common acute lymphocytic leukemia antigen Enkephalinase Neutral endopeptidase 24.11 Skin fibroblast elastase CD_antigen=CD10 |
| Molecular Weight(MW) | 85514 Da |
| Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers |
| Tissue Specificity | This MME antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 728-755 amino acids from the Central region of human MME. |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein |
| Entrez Gene | 4311 |
|---|---|
| Nucleotide Accession | NP_009218.2 NP_000893.2 NP_009219.2 NP_009220.2 |
Application
MME Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the MME antibody detected the MME protein (arrow).
Application
MME Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MME Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
