Application
MME/CD10 (Cat. #AM1949b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MME/CD10 antibody detected the MME/CD10 protein (arrow).| Product Name | MME/CD10 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; Enkephalinase; Neutral endopeptidase 24.11; Skin fibroblast elastase; CD_antigen=CD10 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 307CT12.12.5 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~250 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EPN |
|---|---|
| Alternative Names | MME EPN Neprilysin Atriopeptidase Common acute lymphocytic leukemia antigen Enkephalinase Neutral endopeptidase 24.11 Skin fibroblast elastase CD_antigen=CD10 |
| Molecular Weight(MW) | 85514 Da |
| Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers |
| Tissue Specificity | This MME monoclonal antibody is generated from mouse immunized with MME recombinant protein. |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein |
| Entrez Gene | 4311 |
|---|---|
| Nucleotide Accession | NP_000893.2 |
Application
MME/CD10 (Cat. #AM1949b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MME/CD10 antibody detected the MME/CD10 protein (arrow).| Application Notes | WB:1:100~250 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
