Application
Figure 1: Immunohistochemical analysis of paraffin-embedded human breast ductal myoepithelium(A) and lymph tissue(B), showing cytoplasmic(A) and membrane(B) localization using anti-CD10 antibody with DAB staining(A) and AEC staining(B).| Product Name | CD10 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Clone Number | 2A1H5E1 |
| Host Species | Mouse |
| Tested Applications | IHC |
| IHC:1:200 - 1000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EPN |
|---|---|
| Alternative Names | CD10 |
| Molecular Weight(MW) | 85514 Da |
| Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers |
| Tissue Specificity | Purified recombinant fragment of human CD-10 expressed in E. Coli. |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein |
| Entrez Gene | 4311 |
|---|---|
| Nucleotide Accession | NP_009220.2 |
Application
Figure 1: Immunohistochemical analysis of paraffin-embedded human breast ductal myoepithelium(A) and lymph tissue(B), showing cytoplasmic(A) and membrane(B) localization using anti-CD10 antibody with DAB staining(A) and AEC staining(B).| Application Notes | IHC:1:200 - 1000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human CD-10 expressed in E. Coli. |
