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NFE2L2 Antibody (N-term)

Catalog Number:OM215273
OM215273
Discount Price
OM215273-100ul
1~2 Week
100ul
OM215273-50ul
50ul
OM215273-20ul
20ul
1~2 Week
Product Profile
Product Name NFE2L2 Antibody (N-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms NRF2
Alternative Names NFE2L2
NRF2
Nuclear factor erythroid 2-related factor 2
HEBP1
Nuclear factor
erythroid derived 2
like 2
Molecular Weight(MW) 67827 Da
Function Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region
Tissue Specificity Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle
Cellular Localization Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents
Database Links
Entrez Gene 4780
Nucleotide Accession NP_006155
Application

Application

Western blot analysis of anti-NFE2L2 Antibody (N-term) in Ramos cell line lysates (35ug/lane). Nrf2(arrow) was detected using the purified Pab (1:60 dilution).

Application

Western blot analysis of Nrf2(Nfe2l2)(arrow) using rabbit polyclonal Nrf2(Nfe2l2) Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Nrf2(Nfe2l2) gene (Lane 2) (Origene Technologies).
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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