Application
Western blot analysis of NFE2L2-S40 in T47D(lane 1) and 293(lane 2) cell line lysates (35ug/lane). NFE2L2 (arrow) was detected using the purified Pab.| Product Name | NFE2L2 Antibody (S40) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NRF2 |
|---|---|
| Alternative Names | NFE2L2 NRF2 Nuclear factor erythroid 2-related factor 2 HEBP1 Nuclear factor erythroid derived 2 like 2 |
| Molecular Weight(MW) | 67827 Da |
| Function | Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region |
| Tissue Specificity | Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle |
| Cellular Localization | Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents |
Application
Western blot analysis of NFE2L2-S40 in T47D(lane 1) and 293(lane 2) cell line lysates (35ug/lane). NFE2L2 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
