Application
A. Western blot analysis on A) untreated and B) AP treated HepG2 cell lysates using anti-Phospho-Nrf2 (pS40) RabMAb 1:20,00 dilution.Application
B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-NRF2 RabMAb| Product Name | Nrf2 Antibody Phospho (pS40) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NFE2L2, NRF2, Nuclear factor erythroid 2-related factor 2, Nuclear factor, erythroid derived 2, like 2;HEBP1 |
| Conjugation | Agarose |
| Modification | p-S40 |
| Clonality | Monoclonal |
|---|---|
| Isotype | Cocktail |
| Clone Number | EP1809Y |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:1000~10000 IHC |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | NRF2 |
|---|---|
| Alternative Names | NFE2L2 NRF2 Nuclear factor erythroid 2-related factor 2 Nuclear factor erythroid derived 2 like 2 HEBP1 |
| Molecular Weight(MW) | 67827 Da |
| Function | Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region |
| Tissue Specificity | Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle |
| Cellular Localization | Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents |
| Entrez Gene | 4780 |
|---|
Application
A. Western blot analysis on A) untreated and B) AP treated HepG2 cell lysates using anti-Phospho-Nrf2 (pS40) RabMAb 1:20,00 dilution.
Application
B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-NRF2 RabMAb| Application Notes | WB:1:1000~10000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
