Application
A. Western blot analysis on PC12 cell lysate using anti-NFGR RabMAb (Cat. #AJ1540a).Application
B. Immunohistochemical staining of paraffin-embedded human brain gilioma using anti-NFGR RabMAb (Cat. #AJ1540a).| Product Name | NGFR Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1039Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~2000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TNFRSF16 |
|---|---|
| Alternative Names | NGFR TNFRSF16 Tumor necrosis factor receptor superfamily member 16 Gp80-LNGFR p75 ICD Low affinity neurotrophin receptor p75NTR |
| Molecular Weight(MW) | 45183 Da |
| Function | Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells |
| Tissue Specificity | A synthetic peptide corresponding to residues of human NGFR was used as an immunogen. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 4804 |
|---|
Application
A. Western blot analysis on PC12 cell lysate using anti-NFGR RabMAb (Cat. #AJ1540a).
Application
B. Immunohistochemical staining of paraffin-embedded human brain gilioma using anti-NFGR RabMAb (Cat. #AJ1540a).| Application Notes | WB:1:1000~2000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
