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CD271 Antibody (C-term)

Catalog Number:OM229187
OM229187
Discount Price
OM229187-100ul
1~2 Week
100ul
OM229187-50ul
50ul
OM229187-20ul
20ul
1~2 Week
Product Profile
Product Name CD271 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms TNFRSF16
Alternative Names NGFR
TNFRSF16
Tumor necrosis factor receptor superfamily member 16
Gp80-LNGFR
Low affinity neurotrophin receptor p75NTR
Low-affinity nerve growth factor receptor
p75 ICD
CD_antigen=CD271
Flags: Precursor
Molecular Weight(MW) 45183 Da
Function Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells
Tissue Specificity This CD271 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-381 amino acids from the C-terminal region of human CD271.
Cellular Localization Membrane; Single-pass type I membrane protein
Database Links
Entrez Gene 4804
Nucleotide Accession NP_002498.1
Application

Application

CD271 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CD271 antibody detected the CD271 protein (arrow).

Application

CD271 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD271 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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