Application
NKX3-1 Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the NKX3-1 antibody detected the NKX3-1 protein (arrow).| Product Name | NKX3-1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NKX3.1, NKX3A |
|---|---|
| Alternative Names | NKX3-1 NKX3.1 NKX3A Homeobox protein Nkx-3.1 Homeobox protein NK-3 homolog A |
| Molecular Weight(MW) | 26350 Da |
| Function | Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells |
| Tissue Specificity | Highly expressed in the prostate and, at a lower level, in the testis |
| Cellular Localization | Nucleus. |
| Entrez Gene | 4824 |
|---|---|
| Nucleotide Accession | NP_006158.2 |
Application
NKX3-1 Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the NKX3-1 antibody detected the NKX3-1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
