Application
Figure 1: Western blot analysis using NKX3A mouse mAb against LNCaP (1) cell lysate.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human prostata tissues (A, B) using anti-NKX3A antibody with DAB staining.Application
Figure 3: Flow cytometric analysis of PC-3 cells using anti-NKX3A mAb (green) and negative control (purple).| Product Name | NKX3A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Clone Number | 4H4 |
| Host Species | Mouse |
| Tested Applications | WBIHCFC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NKX3.1, NKX3A |
|---|---|
| Alternative Names | NKX3 BAPX2 NKX3A NKX3.1 NKX3-1 |
| Molecular Weight(MW) | 26350 Da |
| Function | Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells |
| Tissue Specificity | Highly expressed in the prostate and, at a lower level, in the testis |
| Cellular Localization | Nucleus. |
| Entrez Gene | 4824 |
|---|---|
| Nucleotide Accession | NP_006158.2 |
Application
Figure 1: Western blot analysis using NKX3A mouse mAb against LNCaP (1) cell lysate.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human prostata tissues (A, B) using anti-NKX3A antibody with DAB staining.
Application
Figure 3: Flow cytometric analysis of PC-3 cells using anti-NKX3A mAb (green) and negative control (purple).| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human NKX3A expressed in E. Coli. |
