Application
PDCD6 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PDCD6 antibody detected the PDCD6 protein (arrow).| Product Name | PDCD6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDCD6; ALG2; Programmed cell death protein 6; Apoptosis-linked gene 2 protein; Probable calcium-binding protein ALG-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ALG2 |
|---|---|
| Alternative Names | PDCD6 ALG2 Programmed cell death protein 6 Apoptosis-linked gene 2 protein Probable calcium-binding protein ALG-2 |
| Molecular Weight(MW) | 21868 Da |
| Function | Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity) Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity |
| Tissue Specificity | This PDCD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human PDCD6. |
| Cellular Localization | Nucleus membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus. Note=Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules |
| Entrez Gene | 10016 |
|---|---|
| Nucleotide Accession | NP_037364.1 |
Application
PDCD6 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PDCD6 antibody detected the PDCD6 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
