Application
Dot blot analysis of anti-Phospho-PAX6-T373 Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.| Product Name | Phospho-PAX6- T373 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PAX6; AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin |
| Modification | p-T373 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | DB |
| DB:1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AN2 |
|---|---|
| Alternative Names | PAX6 AN2 Paired box protein Pax-6 Aniridia type II protein Oculorhombin |
| Molecular Weight(MW) | 46683 Da |
| Function | Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes |
| Tissue Specificity | Fetal eye, brain, spinal cord and olfactory epithelium. Isoform 5a is less abundant than the PAX6 shorter form |
| Cellular Localization | Nucleus. |
| Entrez Gene | 5080 |
|---|
Application
Dot blot analysis of anti-Phospho-PAX6-T373 Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.| Application Notes | DB:1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
