Application
PPARG Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the PPARG antibody detected PPARG protein (arrow).Application
PPARG Antibody (N-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | PPARG Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPARG; NR1C3; Peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NR1C3 |
|---|---|
| Alternative Names | PPARG NR1C3 Peroxisome proliferator-activated receptor gamma Nuclear receptor subfamily 1 group C member 3 |
| Molecular Weight(MW) | 57620 Da |
| Function | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B- mediated proinflammatory responses |
| Tissue Specificity | Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary |
| Cellular Localization | Nucleus. Cytoplasm. Note=Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner |
| Entrez Gene | 5468 |
|---|---|
| Nucleotide Accession | NP_619725.2 |
Application
PPARG Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the PPARG antibody detected PPARG protein (arrow).
Application
PPARG Antibody (N-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
