Application
Figure 1: Western blot analysis using PPARG monoclonal antibody against truncated PPARG-His recombinant protein(1) and full-length PPARG(aa1-477) transfected CHO-K1 cell lysate(2).| Product Name | PPARG Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; PPARG |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3A4A9, 1E6A1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NR1C3 |
|---|---|
| Alternative Names | CIMT1 NR1C3 PPARG1 PPARG2 PPARgamma PPARG |
| Molecular Weight(MW) | 57620 Da |
| Function | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B- mediated proinflammatory responses |
| Tissue Specificity | Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary |
| Cellular Localization | Nucleus. Cytoplasm. Note=Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner |
| Entrez Gene | 5468 |
|---|---|
| Nucleotide Accession | NP_619726.2 |
Application
Figure 1: Western blot analysis using PPARG monoclonal antibody against truncated PPARG-His recombinant protein(1) and full-length PPARG(aa1-477) transfected CHO-K1 cell lysate(2).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of PPARG(aa170-270) expressed in E. Coli. |
