Application
Western blot analysis of RCC1 in HL-60 cell line lysates (35ug/lane). RCC1 (arrow) was detected using the purified Pab.| Product Name | RCC1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RCC1; CHC1; Regulator of chromosome condensation; Cell cycle regulatory protein; Chromosome condensation protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CHC1 |
|---|---|
| Alternative Names | RCC1 CHC1 Regulator of chromosome condensation Cell cycle regulatory protein Chromosome condensation protein 1 |
| Molecular Weight(MW) | 44969 Da |
| Function | Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly |
| Tissue Specificity | This RCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human RCC1. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Becomes dispersed throughout the cytoplasm during mitosis |
| Entrez Gene | 1104 |
|---|
Application
Western blot analysis of RCC1 in HL-60 cell line lysates (35ug/lane). RCC1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
