RCC1 Antibody (Cat. #AM1961a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RCC1 antibody detected the RCC1 protein (arrow).
RCC1; CHC1; Regulator of chromosome condensation; Cell cycle regulatory protein; Chromosome condensation protein 1
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
332CT2.1.1
Host Species
Mouse
Tested Applications
WB
WB:1:1000~16000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CHC1
Alternative Names
RCC1 CHC1 Regulator of chromosome condensation Cell cycle regulatory protein Chromosome condensation protein 1
Molecular Weight(MW)
44969 Da
Function
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly
Tissue Specificity
This RCC1 monoclonal antibody is generated from mouse immunized with RCC1 recombinant protein.
Cellular Localization
Nucleus. Cytoplasm. Note=Becomes dispersed throughout the cytoplasm during mitosis
RCC1 Antibody (Cat. #AM1961a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RCC1 antibody detected the RCC1 protein (arrow).
Application Notes
WB:1:1000~16000
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.