Application
Figure 1: Western blot analysis using anti-STYK1 mAb against truncated STYK1 recombinant protein(1) and STYK1(aa47-422)-hIgGFc transfected CHO-K1 cell lysate(2).Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (A), normal cerebrum tissues (B), breast infiltrating carcinoma (C) and breast infiltrating carcinoma (D), showing cytoplasmic localization using anti-STYK1/NOK mAb with DAB staining.Application
Figure 3: Immunohistochemical analysis of paraffin-embedded human adrenal tissues using anti-STYK1/NOK mAb with DAB staining.| Product Name | STYK1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NOK; SuRTK106; DKFZp761P1010 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2H2F10 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NOK |
|---|---|
| Alternative Names | NOK SuRTK106 DKFZp761P1010 |
| Molecular Weight(MW) | 47577 Da |
| Function | Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity) |
| Tissue Specificity | Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers |
| Cellular Localization | Membrane; Single-pass membrane protein (Potential) |
| Entrez Gene | 55359 |
|---|---|
| Nucleotide Accession | NP_060893.2 |
Application
Figure 1: Western blot analysis using anti-STYK1 mAb against truncated STYK1 recombinant protein(1) and STYK1(aa47-422)-hIgGFc transfected CHO-K1 cell lysate(2).
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (A), normal cerebrum tissues (B), breast infiltrating carcinoma (C) and breast infiltrating carcinoma (D), showing cytoplasmic localization using anti-STYK1/NOK mAb with DAB staining.
Application
Figure 3: Immunohistochemical analysis of paraffin-embedded human adrenal tissues using anti-STYK1/NOK mAb with DAB staining.| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of STYK1 expressed in E. Coli. |
