Application
TANK Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the TANK antibody detected the TANK protein (arrow).Application
TANK Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TANK Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
TANK Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | TANK Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TANK; ITRAF; TRAF2; TRAF family member-associated NF-kappa-B activator; TRAF-interacting protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ITRAF TRAF2 |
|---|---|
| Alternative Names | TANK ITRAF TRAF2 TRAF family member-associated NF-kappa-B activator TRAF-interacting protein |
| Molecular Weight(MW) | 47816 Da |
| Function | Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF- kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 10010 |
|---|---|
| Nucleotide Accession | NP_004171.2 |
Application
TANK Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the TANK antibody detected the TANK protein (arrow).
Application
TANK Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TANK Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
TANK Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
