Application
ZBTB7B Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ZBTB7B antibody detected the ZBTB7B protein (arrow).Application
Western blot analysis of ZBTB7B (arrow) using rabbit polyclonal ZBTB7B Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ZBTB7B gene.| Product Name | ZBTB7B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ZBTB15, ZFP67, ZNF857B |
|---|---|
| Alternative Names | Zinc finger and BTB domain-containing protein 7B ZBTB7B ZBTB15 ZFP67 ZNF857B |
| Molecular Weight(MW) | 58027 Da |
| Function | Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity) |
| Tissue Specificity | This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human ZBTB7B. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 51043 |
|---|---|
| Nucleotide Accession | NP_056956.2 |
Application
ZBTB7B Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ZBTB7B antibody detected the ZBTB7B protein (arrow).
Application
Western blot analysis of ZBTB7B (arrow) using rabbit polyclonal ZBTB7B Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ZBTB7B gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
