Application
Figure 1: Western blot analysis using ZBTB7B mAb against HEK293(1,2) cell lysate.Application
Figure 2: Immunofluorescence analysis of Hela cells using ZBTB7B mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin| Product Name | ZBTB7B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 7C12 |
| Host Species | Mouse |
| Tested Applications | WBIF |
| WB:1:500 - 2000. IF |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ZBTB15, ZFP67, ZNF857B |
|---|---|
| Alternative Names | THPOK ZFP67 ZBTB15 c-Krox hcKrox ZNF857B DKFZp686G01254 ZBTB7B |
| Molecular Weight(MW) | 58027 Da |
| Function | Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity) |
| Tissue Specificity | Purified recombinant fragment of human ZBTB7B expressed in E. Coli. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 51043 |
|---|---|
| Nucleotide Accession | XP_002345288.1 |
Application
Figure 1: Western blot analysis using ZBTB7B mAb against HEK293(1,2) cell lysate.
Application
Figure 2: Immunofluorescence analysis of Hela cells using ZBTB7B mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin| Application Notes | WB:1:500 - 2000. IF |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human ZBTB7B expressed in E. Coli. |
