Application
Western blot analysis of ZBTB7B Antibody (Center) Pab in mouse brain tissue lysates (35ug/lane). ZBTB7B (arrow) was detected using the purified Pab (1:60 dilution).Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZBTB7B antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | ZBTB7B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ZBTB15, ZFP67, ZNF857B |
|---|---|
| Alternative Names | ZBTB7B ZBTB15 ZFP67 ZNF857B Zinc finger and BTB domain-containing protein 7B Krueppel-related zinc finger protein cKrox T-helper-inducing POZ/Krueppel-like factor Zinc finger and BTB domain-containing protein 15 Zinc finger protein 67 homolog Zinc |
| Molecular Weight(MW) | 58027 Da |
| Function | Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity) |
| Tissue Specificity | This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188~218 amino acids from the center region of human ZBTB7B. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 51043 |
|---|
Application
Western blot analysis of ZBTB7B Antibody (Center) Pab in mouse brain tissue lysates (35ug/lane). ZBTB7B (arrow) was detected using the purified Pab (1:60 dilution).
Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZBTB7B antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
