Application
A. Western blot analysis on Raji cell lysate using anti-Bcl-10 RabMAb (Cat. #AJ1080a), dilution 1:2,000.| Product Name | Bcl-10 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BCL10, CIPER, CLAP, B-cell lymphoma/leukemia 10, CARD-like apoptotic protein |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP605Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CIPER CLAP |
|---|---|
| Alternative Names | BCL10 CIPER CLAP B-cell lymphoma/leukemia 10 CARD-like apoptotic protein |
| Molecular Weight(MW) | 26252 Da |
| Function | Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm, perinuclear region. Membrane raft. Note=Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts |
| Entrez Gene | 8915 |
|---|
Application
A. Western blot analysis on Raji cell lysate using anti-Bcl-10 RabMAb (Cat. #AJ1080a), dilution 1:2,000.| Application Notes | WB:1:500~2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
