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Bcl-10 Antibody (C-term)

Catalog Number:OM227502
OM227502
Discount Price
OM227502-100ul
1~2 Week
100ul
OM227502-50ul
50ul
OM227502-20ul
20ul
1~2 Week
Product Profile
Product Name Bcl-10 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias BCL10, CIPER, CLAP, B-cell lymphoma/leukemia 10, CARD-like apoptotic protein
Key Feature
Clonality Monoclonal
Clone Number EP606Y
Host Species Rabbit
Tested Applications WBIHCIF
WB:1:5000 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms CIPER
CLAP
Alternative Names BCL10
CIPER
CLAP
B-cell lymphoma/leukemia 10
CARD-like apoptotic protein
Molecular Weight(MW) 26252 Da
Function Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1
Tissue Specificity Ubiquitous.
Cellular Localization Cytoplasm, perinuclear region. Membrane raft. Note=Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts
Database Links
Entrez Gene 8915
Application

Application

A. Western blot analysis on Raji cell lysate using anti-Bcl-10 (C-term) RabMAb (Cat. #AJ1080b), dilution 1:5,000.

Application

B. Immunohistochemical analysis of paraffin-embedded human hepatocellular carcinoma using anti-BCL-10 (C-term) RabMAb (Cat. #AJ1080b).

Application

C. Immunofluorescent staining of HeLa cells using anti-BCL-10 (C-term) RabMAb (Cat. #AJ1080b).
Application Notes WB:1:5000 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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