Application
Figure 1: Western blot analysis using anti-calcyclin monoclonal antiobdy against truncated calcyclin recombinant protein.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human brain glioma tissue showing nuclear localization using anti-calcyclin antibody with DAB staining.| Product Name | Calcyclin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | S100A6; 2A9; PRA; 5B10; CABP; CACY |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 7D11 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | S100A6BP SIP |
|---|---|
| Alternative Names | S100A6 2A9 PRA 5B10 CABP CACY |
| Molecular Weight(MW) | 26210 Da |
| Function | May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1) |
| Tissue Specificity | Purified recombinant fragment of calcyclin expressed in E. Coli. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Cytoplasmic at low calcium concentrations. In neuroblastoma cells, after a retinoic acid (RA) induction and calcium increase, it localizes in both the nucleus and cytoplasm. The nuclear fraction may be phosphorylated |
| Entrez Gene | 27101 |
|---|---|
| Nucleotide Accession | NP_055227.1 |
Application
Figure 1: Western blot analysis using anti-calcyclin monoclonal antiobdy against truncated calcyclin recombinant protein.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human brain glioma tissue showing nuclear localization using anti-calcyclin antibody with DAB staining.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of calcyclin expressed in E. Coli. |
