Application
Figure 1: Western blot analysis using anti-Calreticulin polyclonal antiobdy against Hela cell lysate.| Product Name | Calreticulin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RO; CRT; SSA; cC1qR; FLJ26680; CALR |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500 - 2,000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CRTC |
|---|---|
| Alternative Names | RO CRT SSA cC1qR FLJ26680 CALR |
| Molecular Weight(MW) | 48142 Da |
| Function | Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity) |
| Tissue Specificity | Synthetic peptide corresponding to aa(E-E-E-D-V-P-G-Q-A-K-D-E-L-C)of human Calreticulin, conjugated to KLH. |
| Cellular Localization | Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen (By similarity). Note=Also found in cell surface (T cells), cytosol and extracellular matrix Associated with the lytic granules in the cytolytic T-lymphocytes |
| Entrez Gene | 811 |
|---|---|
| Nucleotide Accession | NP_004334.1 |
Application
Figure 1: Western blot analysis using anti-Calreticulin polyclonal antiobdy against Hela cell lysate.| Application Notes | WB:1:500 - 2,000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Synthetic peptide corresponding to aa(E-E-E-D-V-P-G-Q-A-K-D-E-L-C)of human Calreticulin, conjugated to KLH. |
