Application
A. Western blot analysis on (A) mouse brain and (B) rat brain lysates using anti-CaMKII RabMAb (Cat. #AJ1127a), dilution 1:20,000.Application
B. Immunohistochemical staining of paraffin-embedded human brain carcinoma using anti-CaMKII RabMAb (Cat. #AJ1127a).| Product Name | CaMKII Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAMK2A, CAMKA, KIAA0968, Calcium/calmodulin-dependent protein kinase type II alpha chain |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1829Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~5000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAMKA KIAA0968 |
|---|---|
| Alternative Names | CAMK2A CAMKA KIAA0968 Calcium/calmodulin-dependent protein kinase type II alpha chain |
| Molecular Weight(MW) | 54088 Da |
| Function | CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity) |
| Tissue Specificity | A synthetic peptide corresponding to residues on human CaMKII was used as an immunogen. The peptide immunogen is highly conserved between CaMKII-alpha, -beta, -gamma, and -omega. |
| Cellular Localization | Cell junction, synapse, presynaptic cell membrane (By similarity). Cell junction, synapse (By similarity) Note=Postsynaptic lipid rafts (By similarity) |
| Entrez Gene | 815 |
|---|
Application
A. Western blot analysis on (A) mouse brain and (B) rat brain lysates using anti-CaMKII RabMAb (Cat. #AJ1127a), dilution 1:20,000.
Application
B. Immunohistochemical staining of paraffin-embedded human brain carcinoma using anti-CaMKII RabMAb (Cat. #AJ1127a).| Application Notes | WB:1:1000~5000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
