Application
A. Western blot analysis on TF-1 cell lysate using anti-CD-44 RabMAb (Cat. #AJ1163a), dilution 1:5000.Application
B. Immunohistochemical staining of paraffin-embedded human urinary bladder using anti-CD-44 RabMAb (Cat. #AJ1163a).| Product Name | CD44 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, GP90 lymphocyte homing/adhesion receptor;Hermes antigen;Hyaluronate receptor;Heparan sulfate proteoglycan;Epican;CDw44 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR1013Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100000~200000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LHR MDU2 MDU3 MIC4 |
|---|---|
| Alternative Names | CD44 LHR MDU2 MDU3 MIC4 CD44 antigen GP90 lymphocyte homing/adhesion receptor Hermes antigen Hyaluronate receptor Heparan sulfate proteoglycan Epican CDw44 |
| Molecular Weight(MW) | 81538 Da |
| Function | Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs) Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events |
| Tissue Specificity | Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas Expression is repressed in neuroblastoma cells |
| Cellular Localization | Membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges (By similarity) |
| Entrez Gene | 960 |
|---|
Application
A. Western blot analysis on TF-1 cell lysate using anti-CD-44 RabMAb (Cat. #AJ1163a), dilution 1:5000.
Application
B. Immunohistochemical staining of paraffin-embedded human urinary bladder using anti-CD-44 RabMAb (Cat. #AJ1163a).| Application Notes | WB:1:100000~200000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
