Application
Western blot analysis of Fascin Antibody (N-term) in Hela cell line lysates (35ug/lane). Fascin (arrow) was detected using the purified Pab.Application
Fascin Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Fascin Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Fascin Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FSCN1; FAN1; HSN; SNL; Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FAN1 HSN SNL |
|---|---|
| Alternative Names | FSCN1 FAN1 HSN SNL Fascin 55 kDa actin-bundling protein Singed-like protein p55 |
| Molecular Weight(MW) | 54530 Da |
| Function | Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm, cytoskeleton. Cell projection, filopodium. Cell projection, invadopodium. Cytoplasm, cytosol Note=In glioma cells, partially colocalizes with F-actin stress fibers in the cytosol |
| Entrez Gene | 6624 |
|---|
Application
Western blot analysis of Fascin Antibody (N-term) in Hela cell line lysates (35ug/lane). Fascin (arrow) was detected using the purified Pab.
Application
Fascin Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Fascin Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
