Application
Western blot analysis of HIST3H3 Antibody (N-term) in CEM, K562, HL-60 cell line lysates (35ug/lane). HIST3H3 (arrow) was detected using the purified Pab.| Product Name | HIST3H3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | H3FT |
|---|---|
| Alternative Names | HIST3H3 H3FT Histone H3.1t H3/g |
| Molecular Weight(MW) | 15508 Da |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling |
| Tissue Specificity | Expressed in testicular cells. |
| Cellular Localization | Nucleus. Chromosome. |
| Entrez Gene | 8290 |
|---|
Application
Western blot analysis of HIST3H3 Antibody (N-term) in CEM, K562, HL-60 cell line lysates (35ug/lane). HIST3H3 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Data sheet for OM235066