Application
LGALS3 Antibody (C-term) (Cat. #AM1951a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the LGALS3 antibody detected the LGALS3 protein (arrow).| Product Name | LGALS3 Antibody (C-term) (ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Galectin-3;LGALS3;MAC2 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 320CT4.5.2 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500~4000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MAC2 |
|---|---|
| Alternative Names | Galectin-3 LGALS3 MAC2 |
| Molecular Weight(MW) | 26152 Da |
| Function | Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells |
| Tissue Specificity | A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages |
| Cellular Localization | Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface |
| Entrez Gene | 3958 |
|---|---|
| Nucleotide Accession | P17931 NP_002297.2 |
Application
LGALS3 Antibody (C-term) (Cat. #AM1951a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the LGALS3 antibody detected the LGALS3 protein (arrow).| Application Notes | WB:1:500~4000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
