Rabbit Polyclonal antibody to ACE (angiotensin I converting enzyme)This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human ACE. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Mouse
Predicted Reactivity
Human, ChimpanzeeHuman (100%), Chimpanzee (98%)
Concentration
0.2mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CD143 DCP1 angiotensin I converting enzyme ACE1 DCP ICH MVCD3