| Product Name | Activin receptor type II antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [149/1] to Activin Receptor Type II (actRII)The activins and inhibins are glycoproteins that belong to the transforming growth factor-b-like (TGF-b-like) superfamily of growth factors. These factors transduce their signals by interacting with two types of receptor serine/threonine kinases, that phosphorylate members of the SMAD family of transcription factors, thereby promoting their nuclear localization. Useful in the study of activin signal transduction pathways. |
| Immunogen | Recombinant human type-2 activin receptor tyrosine kinase domain. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 149/1 |
| Host Species | Mouse |
| Tested Applications | IPWB |
| For IP (Denatured verified): Use protein G - Use at a dilution of 1:400. For WB: Use at a dilution 1:200. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Activin receptor type II P27037 ACTRII 102581 ACVR2A 92 ACVR2 |
|---|---|
| Target | Activin receptor type II |
| Cellular Localization | Cell Membrane, Cytoplasmic |
| Positive Control | LS174T Cells |
|---|---|
| Application Notes | For IP (Denatured verified): Use protein G - Use at a dilution of 1:400. For WB: Use at a dilution 1:200. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM Phosphate-buffered saline, pH 7.4 containing 0.2% BSA and 0.1% sodium azide |
