| Product Name | AKT1 antibody [PKB-175] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [PKB-175] to Akt1The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB. |
| Immunogen | Synthetic peptide: DSERRPHFPQFSYSAS conjugated to BSA, corresponding to amino acids 461-477 of Human AKT1. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | PKB-175 |
| Host Species | Mouse |
| Tested Applications | WB |
| For WB: Use at a dilution of 1:5,000. Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | RAC, 207, MGC99656, 164730, AKT1, P31749, PRKBA, RAC-ALPHA, RACALPHA, PKB, RAC ALPHA |
|---|---|
| Target | Akt1 |
| Application Notes | For WB: Use at a dilution of 1:5,000. Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Contains 15 mM sodium azide |
