| Product Name | ALK1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [8G33] to ALK1This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008] |
| Immunogen | human TGF RI (ALK1) extra-cellular domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 8G33 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| Western blot(1 : 200-800)|IHC(1: 50): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | TSR-I ALK-1 ORW2 activin A receptor type II-like 1 ALK1 HHT ACVRL1 SKR3 HHT2 ACVRLK1 |
|---|---|
| Target | TGFR-I |
| Tissue Specificity | This antibody recognizes human ALK1 in western blot. |
| Application Notes | Western blot(1 : 200-800)|IHC(1: 50): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
