| Product Name | ATR antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to ATRAtaxia Telangiectasia Mutated (ATM) and Rad 3-related protein (ATR) is a phosphatidylinositol kinase (PK)-related kinase which functions in response to DNA damage and repair as well as at DNA replication checkpoints during the cell cycle. ATR is a member of the DNA-PK kinases closely related to ATM and DNA-PK for which DNA stimulates the observed kinase activity. Chromosomal remodeling proteins have also been reported to associate with ATR complexes. Several known components of the NuRD complex including histone deacetylase 1 (HDAC1), HDAC2, and CHD4. |
| Immunogen | Immunogen was a synthetic peptide, which represented a portion of human ATR and Rad3 related encoded within exon 29 (LocusLink ID 545). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB: Use at a dilution of 0.033 - 0.067 μg/ml. Detects a band of approximately 300 kDa (predicted molecular weight: 307 kDa). Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanMouseXenopus |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FRP1 MEC1 SCKL SCKL1 |
|---|---|
| Target | ATR |
| Molecular Weight(MW) | 291KDa (note) |
| Cellular Localization | Type I membrane protein (Probable). |
| Positive Control | Whole cell lysate from HeLa and U2OS cells |
|---|---|
| Application Notes | For WB: Use at a dilution of 0.033 - 0.067 μg/ml. Detects a band of approximately 300 kDa (predicted molecular weight: 307 kDa). Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 0.1 ml Tris-citrate/phosphate, pH 7-8, with 0.1% sodium azide |
