Application
Western blot analysis of BAFF expression with Jurkat cell lysate.| Product Name | BAFF antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to BAFFBAFF (for B cell Activating Factor) is a novel member in the TNF family. BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNF-alpha and TRAIL, THANK was shown to activate NF-kB and c-Jun N-terminal kinase (JNK) and to induce apoptosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. A 32 kDa full length BAFF and the 18 kDa cleavage fragment can be detected.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BLyS TNFSF20 CD257 TALL1 DTL TALL-1 ZTNF4 TNFSF13B THANK TALL 1 |
|---|---|
| Target | BAFF |
| Tissue Specificity | This antibody is specific for BAFF. |
Application
Western blot analysis of BAFF expression with Jurkat cell lysate.| Application Notes | Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. A 32 kDa full length BAFF and the 18 kDa cleavage fragment can be detected.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
