| Product Name | Calcitonin Receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [30/7-9B4] to Calcitonin ReceptorThis gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
| Immunogen | Synthetic peptide derived from sequence situated on the extra-cellular domain of human calcitonin receptor. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 30/7-9B4 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSICC/IFIHC-PWB |
| FACS:1:200~1:500 ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanRabbitBovine |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CTR CALCR calcitonin receptor CTR1 CT-R CRT |
|---|---|
| Target | Calcitonin Receptor |
| Tissue Specificity | This antibody was raised against the canonical isoform 1 but has been shown to bind to a truncated isoform lacking the N-terminal region of the receptor (Qi et al. 2012). |
| Application Notes | FACS:1:200~1:500 ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | 0.09% Sodium Azide (NaN3) |
