| Product Name | Caldesmon antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [12B5] to CaldesmonMonoclonal anti-Caldesmon may be used for the study of the involvement of caldesmon in contraction, cell movement, shape change, exocytosis and endocytosis. Caldesmon is an actin interacting and calmodulin binding protein found in smooth muscle and other cell types. Caldesmon occurs in both a high molecular weight (120-150 kDa) and a low molecular weight (71-80 kDa) form, depending on the tissue in which it is located. Caldesmon plays a major role in the regulation of smooth muscle and non-muscle contractile events. |
| Immunogen | Duck gizzard caldesmon (heavy chain). |
| Conjugation | Agarose |
| Modification | Acetylated |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 12B5 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCPurifyWB |
| IHC:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DuckHuman |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | L-CAD Q05682 LCAD CDM MGC21352 HCAD CALD1 Caldesmon 114213 800 NAG22 H-CAD L CAD H CAD |
|---|---|
| Target | Caldesmon |
| Tissue Specificity | Reacts with heavy and light forms of caldesmon. Does not cross-react with other proteins. Kd = 10 -12 M. |
| Cellular Localization | Cytoplasmic |
| Application Notes | IHC:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. We recommend to parafilm vials during storage to prevent evaporation of buffer. |
| Storage Buffer | PBS with 0.1% sodium azide |
