Application
Surface staining of human peripheral blood cells with anti-human CD11a (MEM-25): PE .| Product Name | CD11a antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [MEM - 25] to CD11aCD11a is a glycoprotein with a molecular weight of 26 kDa expressed in combination with the CD18 beta chain. The complex is a member of the beta2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM-2, ICAM-3. CD11a is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T-cells. Anti-CD11a from I21/7 reacts with 97% of thymocytes, 95% of blood lymphocytes, 70% of bone marrow cells of all mouse strains tested. |
| Immunogen | Leucocytes from a pacient suffering from a LGL-type leukaemia. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | MEM-25 |
| Host Species | Mouse |
| Tested Applications | PurifyFACSIP |
| Flow Cytometry, Immunoprecipitation, Functional Applications (blocks binding of LFA-1 complex to ICAM-1. Suitable MAb for affinity purification of LFA-1 from lecocytes).: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein A |
| Gene Synonyms | 153370 3683 LFA1A LFA-1 CD11A LFA1 ITGAL P20701 LFA 1 |
|---|---|
| Target | CD11a |
| Tissue Specificity | a-subunit (CD11a) of human LFA-1. |
| Cellular Localization | Cell Membrane and Plasma membrane |
Application
Surface staining of human peripheral blood cells with anti-human CD11a (MEM-25): PE .| Application Notes | Flow Cytometry, Immunoprecipitation, Functional Applications (blocks binding of LFA-1 complex to ICAM-1. Suitable MAb for affinity purification of LFA-1 from lecocytes).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline pH 7.4 containing 15mM sodium azide |
