| Product Name | CD11a antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [MEM - 83] to CD11aCD11a is a glycoprotein with a molecular weight of 26 kDa expressed in combination with the CD18 beta chain. The complex is a member of the beta2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM-2, ICAM-3. CD11a is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T-cells. Anti-CD11a from I21/7 reacts with 97% of thymocytes, 95% of blood lymphocytes, 70% of bone marrow cells of all mouse strains tested. |
| Immunogen | Tissue / cell preparation (Human). Peripheral blood lymphocytes. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | MEM-83 |
| Host Species | Mouse |
| Tested Applications | BlockingFACS |
| FACS: Use at an assay dependant concentration. FuncS: Use at an assay dependant concentration. Induces high-affinity conformation of LFA-1. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | 153370 3683 LFA1A LFA-1 CD11A LFA1 ITGAL P20701 LFA 1 |
|---|---|
| Target | CD11a |
| Tissue Specificity | The antibody recognizes an unique epitope on CD11a antigen (LFA-1 alpha chain) implicated in activation of LFA-1 complex. |
| Cellular Localization | Cell Membrane and Plasma membrane |
| Application Notes | FACS: Use at an assay dependant concentration. FuncS: Use at an assay dependant concentration. Induces high-affinity conformation of LFA-1. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline pH 7.4 containing 15mM sodium azide |
