| Product Name | CD130 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [B-T2] to CD130The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2010] |
| Immunogen | Natural soluble CD130. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | B-T2 |
| Host Species | Mouse |
| Tested Applications | ELISAFACS |
| Flow Cytometry: Max Dilution 0.2ug/106cells Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IL6ST CDW130 GP130 interleukin 6 signal transducer (gp130 oncostatin M receptor) IL-6RB |
|---|---|
| Target | CD130 |
| Tissue Specificity | This antibody recognizes soluble and membrane bound gp130 receptor, also known as CD130. |
| Application Notes | Flow Cytometry: Max Dilution 0.2ug/106cells Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
