Application
FACS analysis of human peripheral blood monocytes using CD18 antibody [MEM-148].Application
FACS analysis of human peripheral blood granulocytes using CD18 antibody [MEM-148].| Product Name | CD18 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [MEM-148] to CD18The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | MEM-148 |
| Host Species | Mouse |
| Tested Applications | FACSIPWBFunctional Assay |
| Western Blotting: Max Dilution Non-reducing conditions Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | integrin beta 2 (complement component 3 receptor 3 and 4 subunit) MAC-1 LFA-1 MF17 ITGB2 LCAMB MFI7 LAD |
|---|---|
| Target | CD18 |
| Tissue Specificity | This antibody recognizes an epitope on the human CD18 molecule that is hidden in the CD11/CD18 heterodimer on resting cells. |
Application
FACS analysis of human peripheral blood monocytes using CD18 antibody [MEM-148].
Application
FACS analysis of human peripheral blood granulocytes using CD18 antibody [MEM-148].| Application Notes | Western Blotting: Max Dilution Non-reducing conditions Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
