Application
IHC-P analysis of human pituatory using CD3 antibody.Application
IHC image using - Detection of CD3 by IHC in human tonsil| Product Name | CD3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to CD3T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. |
| Immunogen | Synthetic peptide (Human) conjugated to BSA. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIHC-FIHC-P |
| IHC: This antibody may be diluted to a titer of 1:10-1:50 in an ABC method. Staining Protocol: We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | T3E 186740 P09693 T3D 916 CD3-GAMMA 917 CD3GAMMA TCRE P20963 186830 186780 P04234 CD3ZETA CD3H CD3Q CD3E CD3 CD3-DELTA TCRZ 919 CD3Z CD3G 915 CD3-ZETA 186790 T3G CD3D P07766 CD3DELTA CD3 ZETA CD3 GAMMA CD3 DELTA |
|---|---|
| Target | CD3 |
| Tissue Specificity | This antibody reacts with a intracytoplasmic portion of the CD3 antigen on T cells. It stains T cells in the cortex as well as the medulla of the thymus and lymphoid tissues. This antibody also labels T cell neoplasms, malignant histiocytes and Hodgkin's lymphoma. |
| Cellular Localization | Type I membrane protein. |
Application
IHC-P analysis of human pituatory using CD3 antibody.
Application
IHC image using - Detection of CD3 by IHC in human tonsil| Application Notes | IHC: This antibody may be diluted to a titer of 1:10-1:50 in an ABC method. Staining Protocol: We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. |
| Storage Buffer | PBS with sodium azide and 1% BSA |
