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CD3 antibody

Catalog Number:OM244876
Baboon;Cat;Dog;Horse;Human;Monkey;Mouse;Pig;Rabbit;Rat;Sheep;Woodchuck
FACS;IHC;IHC-P;WB
OM244876
Discount Price
OM244876-100ul
1~2 Week
100ul
OM244876-50ul
50ul
OM244876-20ul
20ul
1~2 Week
Product Profile
Product Name CD3 antibody
Antibody Type Primary Antibodies
Product description Rabbit monoclonal [SP7] to CD3The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq]
Immunogen Synthetic peptide: KAKAKPVTRGAGA, corresponding to amino acids 156-168 of Human CD3 epsilon chain.
Conjugation Agarose
Modification Acetylated
Key Feature
Clonality Monoclonal
Isotype IgG
Clone Number SP7
Host Species Rabbit
Tested Applications FACSIHCIHC-PWB
WB:1:500~1:2000
IHC-P:1:50~1:200
Species Reactivity BaboonCatDogHorseHumanMonkeyMousePigRabbitRatSheepWoodchuck
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms T3E
186740
P09693
T3D
916
CD3-GAMMA
917
CD3GAMMA
TCRE
P20963
186830
186780
P04234
CD3ZETA
CD3H
CD3Q
CD3E
CD3
CD3-DELTA
TCRZ
919
CD3Z
CD3G
915
CD3-ZETA
186790
T3G
CD3D
P07766
CD3DELTA
CD3 ZETA
CD3 GAMMA
CD3 DELTA
Target CD3
Tissue Specificity This antibody is suitable for staining normal and neoplastic T cells in formalin-fixed, paraffin-embedded tissues.
Cellular Localization Type I membrane protein.
Application

Application

Formalin fixed paraffin embedded human tonsil stained with CD3antibody

Application

Human Renal Cell Carcinoma stained with anti-CD3 antibody

Application

Human Uterus stained with anti-CD3 antibody

Application

Human Lung Squamous Cell Carcinoma stained with anti-CD3 antibody

Application

Human Breast Ductal Carcinoma stained with anti-CD3 antibody

Application

Human Cervix stained with anti-CD3 antibody

Application

Human Reactive Lymph Node stained with anti-CD3 antibody

Application

Human HK Lymphoma stained with anti-CD3 antibody

Application

Human Tonsil stained with anti-CD3 antibody

Application

Human Thymus stained with anti-CD3 antibody

Application

Flow cytometric analysis of rabbit anti-CD3 (SP7) antibody in Jurkat (green) compare to negative control of rabbit IgG (blue)

Application

Western Blot analysis of Jurkat cell lysate with CD3 antibody
Positive Control Tonsil
Application Notes WB:1:500~1:2000
IHC-P:1:50~1:200
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Storage Buffer TCS containing 0.1% sodium azide
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