Application
Application| Product Name | CD36 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [VM58] to CD36Functional studies on CD36. |
| Immunogen | Human monocytes. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | VM58 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHCIHC-F |
| ICC/IF:1:50~1:100 IHC:1:10~1:50 IHC-F:1:10~1:20 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Gene Synonyms | GPIV FAT GP3B 948 SCARB3 173510 CD36 PASIV P16671 GP4 |
|---|---|
| Target | CD36 |
| Tissue Specificity | The monoclonal antibody VM58 is directed against the CD36 antigen, a 90kD glycoprotein, also called GP IIIb expressed on human platelets. The GP IV (GP IIIb) molecule has been shown to function as thrombospondin receptor on platelets and monocytes and as receptor for Plasmodium falciparum infected erythrocytes. The monoclonal antibody reacts with platelets, monocytes, macrophages, erythroblasts and (weakly) with B-cells. In immunohistology the monoclonal antibody reacts with some endothelial cells, adipocytes and the granular layer of the skin. The antibody VM58 induces Fc-receptor-dependent platelet aggregation after binding to platelet. The heterogeneity of the response found in healthy individuals is dependent on the polymorphism of the Fc RII on platelets. |
| Light Chain Type | kappa |
Application
Application| Application Notes | ICC/IF:1:50~1:100 IHC:1:10~1:50 IHC-F:1:10~1:20 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4oC short term. For extended storage aliquot and store at -20oC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS with approximately 0.2 mg antibody/ml and sodium azide. |
