| Product Name | CD42b antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [SZ2] to CD42bCD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF. |
| Immunogen | Tissue / cell preparation: Human washed platelets. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | SZ2 |
| Host Species | Mouse |
| Tested Applications | FACS |
| For FACS: Use 2μg for 5x10^6 cells. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | P07359 MGC34595 CD42B CD42balpha GP1B GP1BA 177820 BSS CD42b-alpha 2811 CD42b alpha |
|---|---|
| Target | CD42b |
| Tissue Specificity | Reacts with glycoprotein Ib on megakaryocytes and platelets. Inhibits the ristocetin dependent binding of Von Willebrand factor to platelets and ristocetin induced platelet agglutination. Inhibits platelet aggregation induced by Type I collagen and platelet activating factor (PAF). Immunoprecipitates the components of glycoprotein Ib complex. |
| Cellular Localization | Cell Membrane and Plasma membrane |
| Application Notes | For FACS: Use 2μg for 5x10^6 cells. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2 containing 1mg/ml BSA and 0.1% sodium azide |
