| Product Name | CD81 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [M38] to CD81CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells – e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.Entrez Gene (human): 11p15.5 |
| Immunogen | MOLT-4 (human T-ALL cell line) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | M38 |
| Host Species | Mouse |
| Tested Applications | FACSICC/IFIHC-PIPWBFunctional Assay |
| Functional: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-. Positive human T-cell lines: |
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| Species Reactivity | HumanCatRabbit |
| Concentration | 1mg/ml |
| Gene Synonyms | S5.7 TAPA1 TSPAN28 |
|---|---|
| Target | CD81 |
| Tissue Specificity | The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells. |
| Application Notes | Functional: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-. Positive human T-cell lines: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8°C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles. |
| Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
