Application
Detection of CFTR by IHC in Human PancreasApplication
WB: T84 cell lysate probed with anti-CFTR (0.5 µg/ml)| Product Name | CFTR antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [M3A7] to CFTRCystic Fibrosis Transmembrane Regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD) and one R domain. It is structurally similar to multidrug resistance protein (Mdr1). CFTR is found in the apical membranes of epithelia within the pancreas, intestine, bile duct, sweat gland and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. |
| Immunogen | Recombinant protein encoding NBF 2 domain of human CFTR. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | M3A7 |
| Host Species | Mouse |
| Tested Applications | IHCIHC-FIHC-PIPWB |
| Immunohistochemistry: Use at a dilution of 1/50 - 1/100 (ABC method) : |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CFTR P13569 ABCC7 TNRCFTR MRP7 1080 TNR-CFTR 219700 dJ760C5.1 CF ABC35 TNR CFTR |
|---|---|
| Target | CFTR |
| Tissue Specificity | This antibody reacts with a protein of 165-170 kDa. |
| Cellular Localization | Cell membrane. |
Application
Detection of CFTR by IHC in Human Pancreas
Application
WB: T84 cell lysate probed with anti-CFTR (0.5 µg/ml)| Positive Control | Pancreas |
|---|---|
| Application Notes | Immunohistochemistry: Use at a dilution of 1/50 - 1/100 (ABC method) : |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | PBS containing 0.1% sodium azide |
