Mouse monoclonal to beta subunit Cholera ToxinCholera toxin (CT) acts by transfer of ADP-ribose from intracellular NAD to the alpha chain of a trimeric G protein that functions to stimulate adenylate cyclase resulting in the increase of host cell cAMP. CT binds via the beta subunits to the GM1 ganglioside. Gangliosides are glycolipids that also contain oligosaccharides with one or more sialic acid residues.
Immunogen
Purified beta subunit of cholera toxin.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
ELISAIHC
Dilute in PBS or medium which is identical to that used in the assay system. Average indirect ELISA titer is1:1,000,000.
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein A
Target Information
Gene Synonyms
Cholera enterotoxin beta chain CTXB TOXB VC1456
Target
Cholera Toxin B subunit
Tissue Specificity
This antibody reacts with the beta subunit of cholera toxin and does not cross-react with the alpha subunit.
Cellular Localization
Secreted
Application Notes
Dilute in PBS or medium which is identical to that used in the assay system. Average indirect ELISA titer is1:1,000,000.
Additional Information
Form
Liquid
Storage Instructions
Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.