| Product Name | Complement MASP3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4F19] to Complement MASP3This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010] |
| Immunogen | Human recombinant Complement MASP3 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 4F19 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB(1:500-1000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 3MC1 MAP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) MASP MASP1 CRARF1 MASP3 PRSS5 CRARF RaRF MA |
|---|---|
| Target | Complement MASP3 |
| Tissue Specificity | This antibody was selected for its ability to detect human Complement MASP3 |
| Application Notes | WB(1:500-1000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
